Queensland will be looking to regain the Shield that has resided in the Sunshine state for the large percentage of the past decade.
Mainstays such as Cronk, Smith, Slater, Thurston, Holmes, Boyd and Thaiday have all moved on from the rep set up in the past two years, meaning there's a chance we'll see some new blood in 2019.
A lot depends on where Kevin Walkers plays his big three stars in Morgan, Munster and Ponga. You'd have to think they'd be fullback, six and seven, with Ben Hunt at nine or in the utility spot.
The forwards look set for a shake up, while the centre position is possibly open for the first time in a long time.
Truthfully I can't see too many grand changes but below are a few options for possible debuts come Origin One. In no particular order, here are some possible names.
1. Edrick Lee
Corey Oates is the obvious replacement for Valentine Holmes, with Dane Gagai on the other wing, but if either are injured, name me one more in form Queensland winger? Lee has started the season on fire and had a brilliant year in 2018 with the Sharks. He's spent time in Origin camp as a shadow player and stranger things have happened. Yes, at this stage, it looks a long shot, but as I said, his form is right where it needs to be. Whether or not he can keep that going for the next 8 or-so rounds is another question, but I'm a fan of the Newcastle winger.