The Manly Sea Eagles announced on Wednesday the gun pairing of Jake Trbojevic and Addin Fonua-Blake will have clean-out shoulder surgeries.
The recovery time is expected to be four months, therefore putting the early rounds of the 2020 NRL season in doubt for both men.
This may no put a slight dampener on what looks to be enthralling encounters between the Storm and the Roosters in the first two rounds.
NRL.com said both men pushed through pain to finish off the 2019 as Des Hasler's team were plagued by injury.
Trbjojevic and Fonua-Blake follow on from Tom Trbojevic (pectoral), Joel Thompson (arm), Curtis Sironen (foot) and Teniela Paseka (knee) who all had surgery to add their seasons.
Manase Fainu is another player missing after shoulder surgery as he also battles criminal charges.
Fainu is declining allegations he stabbed a man in Sydney's south west.
He was denied bail as he faces another bail hearing set for Monday, November 11