Cowboys vs Bulldogs
Jake Clifford was a late withdrawal against the Panthers last week, but should return to the side this weekend, with John Asiata likely to head back to the bench.
Suspension has ruled out Reimis Smith, with a battle between Jordan Okunbur and the untried Morgan harper set to take place to step in and cover for Smith.
Warriors vs Rabbitohs
Karl Lawton should return from a shoulder injury.
The Bunnies will be without James Roberts, meaning Wayne Bennett will need to make at least one change to his side this weekend. Alex Johnston could return, but Bennett may decide to leave him until the final round.
Broncos vs Eels
The Broncos are set to line up 1-17 despite losing last weekend.
Nathan Brown will miss the rest of the Eels' home-and-away season after copping a two-week ban. Peni Terepo looks set to replace him in the side.
Knights vs Titans
Connor Watson will be fit to return at hooker, meaning Danny Levi will have to make way, whether that be on the bench or out of the side altogether.
Jesse Arthars will need to pass concussion protocol in order to be deemed fit to play, although he'll likely be named on Tuesday afternoon.
Sea Eagles vs Storm
Joel Thompson will undergo surgery on Tuesday for a broken arm, and will miss the next 4-6 weeks. Moses Suli also looks set to miss, with Brad Parker and Curtis Sironen set to return from injuries.
Melbourne will be missing Will Chambers, who won't return until the finals after suffering an ankle injury. Curtis Scott is set to replace him. Brandon Smith will need to pass concussion protocol in order to play.
Roosters vs Panthers
Latrell Mitchell missed his side's clash with the Dragons, but should return this weekend. Billy Smith should head straight back out of the side for him. Boyd Cordner is nearing a return, and this weekend could be it. Jake Friend is targeting next week for his comeback.
Jarome Luai could come into the side, although the Panthers won't be forward into a chance in the backline after Brent Naden was only fined for a high tackle.
Sharks vs Raiders
Sosaia Feki and Jack Williams are both set to miss for the Sharks, with Jayson Bukuya set to be brought into the side.
Joey Leilua will likely miss through suspension, which would allow Bailey Simonsson to take his place.
Dragons vs Tigers
Ben Hunt and Patrick Kaufusi could return for this weekend's clash, which could see Corey Norman moved to fullback.
Moses Mbye is nearing a return, and is set to be named for this clash.