Eels v Rabbitohs
The Eels could welcome back hooker Kaysa Pritchard from a groin injury, while Manu Ma'u will also be a welcome addition after missing Parramatta's win over the Cowboys for the birth of his child.
South Sydney will bring back their Origin I stars, with Greg Inglis, Damien Cook, Angus Crichton and Dane Gagai all to return after resting last weekend.
Cowboys v Warriors
Michael Morgan was rested last week after Origin I as he continues to battle an ongoing groin injury, with Lachlan Coote set to make way for Morgan.
Roger Tuivasa-Sheck was a late withdrawal last week, but should return from the ankle injury that kept him sidelined. Gerard Beale could make way if he returns.
Roosters v Panthers
Blues captain Boyd Cordner will return after he was rested last week, with his inclusion set to be the only change for Sydney.
Penrith have lost Viliame Kikau to a knee injury, and he could miss the next month with that complaint. Jack Hetherington returns from a one-game suspension.
Bulldogs v Titans
Kieran Foran will miss another week with a toe injury, with Jeremy Marshall-King to stay at No.6.
Jarrod Wallace is set to miss the game through suspension, which leaves the Titans' forward pack a little bare. Max King has a dislocated shoulder and will not play, while Moeaki Fotuaika must prove he's over a concussion before taking the field.
Dragons v Sea Eagles
The Dragons are sitting pretty on top of the NRL ladder, and don't have many injury concerns to worry about. They should be 1-17 when they name their side to face the Sea Eagles on Tuesday afternoon.
Apisai Koroisau will miss the next 8-10 weeks with a broken foot, and will likely be replaced by Lewis Brown at hooker.
Sharks v Broncos
Josh Dugan is still under an injury cloud, and will likely miss another week through injury.
James Roberts should return to face Brisbane after he was rested last week, which will likely see Tom Opacic fall back out of the 17.
Knights v Storm
Jamie Burhrer will miss, while Daniel Saifiti will also join him on the sidelines with a foot injury that should see him miss the next month.
Jesse Bromwich will miss with a hamstring injury, while Dale Finucane could also be unavailable with his thumb injury taking a while to heal. Sam Kasiano, Curtis Scott and Will Chambers will all return from suspension.
Tigers v Raiders
Benji Marshall will be unavailable for the next six weeks with a calf injury, which will see Josh Reynolds permanently take his spot in the halves.
Jordan Rapana's hamstring injury will see him miss out, with Michael Oldfield the obvious replacement. Suspension helps and hinders the Raiders, with Joseph Tapine to return from a ban, while Charlie Gubb could miss two weeks through suspension. Joseph Leilua needs to prove his fitness after suffering a concussion last time out.