SYDNEY, AUSTRALIA - JULY 03: Boyd Cordner passes during a New South Wales Blues State of Origin training session at Coogee Oval on July 3, 2018 in Sydney, Australia. (Photo by Mark Kolbe/Getty Images)

The Blues have ruled out Boyd Corner for the remainder of the State of Origin series.

The NSW skipper is standing down on medical advice after suffering a string of concussions during the season.

According to The Daily Telegraph's Phil Rothfield, the Blues will confirm Cordner's omission later this afternoon.

He is expected to leave the Blues camp later this afternoon and miss the rest of the series, with James Tedesco to take over the captaincy.

Angus Crichton is set to start in place of Corder in the second-row, while Nathan Brown is set to make his Origin debut for the Blues.

The Origin teams for Game 2 will be announced at 4pm on Friday AEST.

Game 2 stands as a must-win for Brad Fittler's team after their shock 14-18 Game 1 loss.