Following the completion of the fourth round of the 2025 NRL season, several teams will look to change up their team, while others will enter Round 5 with the exact same line-up.

Nathan Cleary (Penrith Panthers), Thomas Hazelton (Cronulla Sharks) and Nelson Asofa-Solomona (Melbourne Storm) are just a few players that are set to be available for selective heading into Round 5.

However, while some return, the likes of Brian To'o (Penrith Panthers), Tom Trbojevic (Manly Sea Eagles), Jarome Luai (Wests Tigers), Kayal Iro (Cronulla Sharks) and Alex Johnston (South Sydney Rabbitohs) have been ruled out for this week.

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Penrith Panthers vs North Queensland Cowboys

NRL Round 2, 2025: Penrith Panthers vs Sydney Roosters
SYDNEY, AUSTRALIA - MARCH 14: Brian To'o during the round two NRL match between Penrith Panthers and Sydney Roosters at CommBank Stadium, on March 14, 2025, in Sydney, Australia. (Photo by Joshua Davis/Zero Digital Sports)

Penrith Panthers

After suffering their third consecutive loss last week, Ivan Cleary is bound to make some changes to his side, which will be boosted by the inclusions of Nathan Cleary and Dylan Edwards (he remains a 50/50 chance).

However, winger Brian To'o will spend up to a month on the sidelines with a hamstring injury and so will Scott Sorensen (concussion) for at least one week.

“Nathan will be back, but ‘Bizza' (To'o) won't be. Hopefully Dyl will be,” Ivan Cleary said.

“He (To'o) will be out for a few weeks.”

The McLean brothers - Casey and Jesse - firm as his obvious replacement.

Projected Round 5 Team: 1. Dylan Edwards 2. Jesse McLean 3. Izack Tago 4. Paul Alamoti 5. Casey McLean 6. Jack Cole 7. Nathan Cleary 8. Moses Leota 9. Mitch Kenny 10. Lindsay Smith 11.  Isaiah Papali'i 12. Liam Martin 13. Isaah Yeo 14. Brad Schneider 15. Luron Patea 16. Liam Henry 17. Luke Garner

 2025-04-04T07:00:00Z 
 
 
 
CommBank Stadium
PEN   
18
FT
22
   NQL
   Crowd: 10,320
MATCH CENTRE ▶︎   

North Queensland Cowboys

After securing their first win of the season last week against the Raiders, Todd Payten isn't forced into any changes for this week and is set to run the same line-up as they attempt to make it back-to-back victories.

Predicted Round 5 Team: 1. Scott Drinkwater 2. Robert Derby 3. Jaxon Purdue 4. Viliami Vailea 5. Murray Taulagi 6. Tom Dearden 7. Jake Clifford 8. Jordan McLean 9. Reece Robson 10. Jason Taumalolo 11. John Bateman 12. Kai O'Donnell 13. Reuben Cotter 14. Sam McIntyre 15. Jeremiah Nanai 16. Griffin Neame 17. Coen Hess

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