Parramatta Eels v Canterbury Bulldogs
Kaysa Pritchard (knee) and Beau Scott (bicep) will both miss the rest of Parramatta's season, with Cameron King and Tepai Moeroa likely to be named as their replacements.
Josh Hoffman and Kirisome Auva'a are both fit for selection once again but may not be able to break into the Eels' squad after a strong performance from the outside backs in their last win in Round 15.
Brett Morris failed to back up for the Bulldogs last week following Origin 2 but will return to action against the Eels, with Kerrod Holland likely to make way.
Gold Coast Titans v St George Illawarra Dragons
Chris McQueen will return for the Titans after he was a late withdrawal last weekend, while five-eighth Tyrone Roberts could be in line for a return from a shoulder injury, and would replace last week's debutant in Jamal Fogarty.
Jack de Belin will return from suspension and slot straight back into the Dragons' side, while Euan Aitken should play after recovering from his hamstring injury with Kurt Mann the likely player to move to the bench.
Brisbane Broncos v Melbourne Storm
Korbin Sims missed last week's game with a groin injury after being a late withdrawal from the side. Sam Thaiday must pass a concussion test if he's to be deemed fit to play.
Cameron Smith, Cooper Cronk and Billy Slater will all be named for the Storm after missing last weekend's game due to soreness but are still touch and go to play. Will Chambers was concussed during Origin 2 and will need to prove his fitness.
Sydney Roosters v Cronulla Sharks
Boyd Cordner could return to the Roosters' line-up after a calf injury sustained in Origin Two saw him miss their clash with the Storm last weekend.
The Sharks will have to look even further down the line in their quest for a hooker, after Jayden Brailey broke his jaw last weekend. With James Segeyaro out until Round 19 and their two other hooker released to the Warriors (Manaia Cherrington) and the Super League (Daniel Mortimer), Fa'amanu Brown will likely rep the number nine jersey on Saturday, while Joseph Paulo could play minutes at hooker off the bench.
Manly Sea Eagles v New Zealand Warriors
The Sea Eagles will be without Curtis Sironen, with the forward expected to miss a long period of time with an upper body injury.
Kieran Foran will be named but may not make his return this weekend, with their match against the Panthers following next week's bye the most likely return date. Nathaniel Roache could replace Isaac Luke after the hooker went down with an injury last weekend.
Canberra Raiders v North Queensland Cowboys
The Raiders should go in unchanged despite going down to the Broncos at home last weekend.
With Johnathan Thurston out for the rest of the season with a shoulder injury, Kyle Laybutt and Te Maire Martin will battle it out for a spot in the halves.
Newcastle Knights v Wests Tigers
Jamie Buhrer and Sam Stone could return to the Knights' line-up following foot and sternum injuries respectively, with Nathan Ross (fullback) and Dane Gagai (centre) expected to stay in those positions after Ross' hat-trick last weekend.
James Tedesco is nearing a return to the Tigers' line-up, while Tim Grant will come back into the side after serving his suspension.
South Sydney Rabbitohs v Penrith Panthers
Sam Burgess will be named for the Rabbitohs, while Aaron Gray should return in the centres, after Hymel Hunt was confirmed to be out for an extended period with a hand injury.
James Fisher-Harris may be fit enough to return for the Panthers this weekend, with Mitch Rein expected to hold down the hooker spot with Peter Wallace still weeks away from a return.
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