Wesser, a veteran of 14 seasons in the National Rugby League, has played 218 NRL games to date including 177 matches for the Penrith Panthers between 1998 and 2008, and 41 games for the South Sydney Rabbitohs since moving to the club in 2009.
Wesser has achieved some of the highest honours in the sport playing four State of Origin matches for Queensland in 2004 and 2006; won an NRL premiership with the Panthers in 2003; and represented the Indigenous Dreamtime team in 2008 at the Rugby League World Cup.
Rabbitohs CEO Shane Richardson paid tribute to Rhys.
“Rhys is one of the game’s greatest role models off the field, and one of the game’s most electrifying players on the field, and he has been this for many seasons,” Mr Richardson said.
Wesser says he is looking forward to starting the next chapter of his life.
“Season’s end is the right time to hang up the boots and look towards the next phase of my life,” Wesser said.
“I’ve enjoyed every minute of my career and I’ve been lucky enough to play for my state, to represent my people at the World Cup, and to have had the feeling of winning a premiership.”